Vape vs Cigarette Nicotine: How Many 5% Vape Puffs Equal One Cig? How Many Vape Puffs Equal One Cigarette? CIV Plus 1 electronic cigarette pod is roughly equal to 20 cigarettes' worth of nicotine, or 200 puffs. That's a lot! Make the choice not to let nicotine control your life. #EliminateTobacco and put The nicotine content of many disposable vapes is equivalent to a pack of 20 cigarettes. If you don't smoke, don't vape. #NoSmokingMonth