The nicotine content of many 2ml nicotine pods for multi pod devices is equivalent to a pack of 20 cigarettes. If you don't smoke, don't vape. And if you are smoking 20mg Vape vs Cigarettes: How Many Puffs Equal 1 Cigarette Vapesourcing How Many Puffs of a 20MG Vape Is Equal to a Cigarette? Say no to vaping. 10 15 vape puffs are roughly equivalent to one cigarette. We want to encourage and support families to have open and engaging conversations with young people to