Smoke alarms & e cigarettes in hotel rooms Fire alarm? Will a Vape Set Off a Fire Alarm? What to Know Your guests aren't the only ones checking in. So are their vape pens. With over 13 million regular vapers in the U.S. alone, unauthorized vaping is a major operational risk for hotels. A pair of hackers found that a vape detector often found in high school bathrooms contained microphonesand security weaknesses that could allow someone to turn it into a secret listening device.