Even when vapes are marketed as nicotine free, they may contain small amounts of nicotine. This may be due to cross contamination during manufacturing or deceptive practices. Some manufacturers may use synthetic (man made, lab created) Differences in flavourant levels and synthetic coolant use between USA, EU and Canadian Juul products Tobacco Control JUUL Pods Review Including the New Rich Tobacco Flavour Ecigclick F.D.A. Approves Juul Vapes After Yearslong Delay The New York Times